The anti-human CD3-Fab Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The anti-human CD3-Fab Antibody has been validated for the following applications: Flow Cytometry, and Western Blot.
Description
Information: The human CD3/T cell receptor (TcR) complex is made up of at least five CD3 proteins (gamma, delta, epsilon, h, z) in association with either alpha/beta or gamma/delta proteins of the TcR. The TcR recognizes antigens in association with MHC molecules after which protein chains of the CD3 complex mediate activation signals triggered by TcR antigen binding. CD3 is expressed on greater than 95% of circulating human peripheral T cells. Antibody UCHT1 recognizes the 20 kd episilon chain of the CD3 molecule complex. Antibody UCHT1 will activate T cells expressing CD3epsilon